In this paper we present a recently developed tool named BrainAssist, which can be used for the study and analysis of brain abnormalities like Focal Cortical Dysplasia (FCD), Heterotopia and Multiple Sclerosis (MS). For the analysis of FCD and Heterotopia we used T1 weighted MR images and for the analysis of Multiple Sclerosis we used Proton Density (PD) images. 52 patients were studied. Out of 52 cases 36 were affected with FCDs, 6 with MS lesions and 10 normal cases.

Preoperative MR images were acquired on a 1.5-T scanner (Siemens Medical Systems, Germany). The acquired 3D MRI data set consist of approximately 120 T1 weighted coronal slices with flip angle 15°, matrix size 256 x 224, FOV 256, thickness 1.5 mm and pixel spacing 0.89 mm. Key words: BrainAssist, Brain Segmentation, Focal Cortical Dysplasia, Heterotopia, MR images, Multiple Sclerosis, Volume Calculation.